Following the 2011 uprisings that ousted Hosni Mubarak in Egypt, the Muslim Brotherhood (MB) enjoyed an unprecedented level of political participation, seizing both a majority in parliament and the presidency of the country in 2012. This paper explores how the Brotherhood’s opportunity for greater political involvement affected its female members, the Muslim Sisters. In particular, it reflects on the extent to which the group was willing to include women in its political affairs, the role that women played in the political spaces seized by the movement, and the gender discourse promoted by the Sisters. The data presented draws from the author’s analysis of MB’s primary video material and literature 2 published online between 2011 and 2013. These are complemented by the scholar’s observations and interviews with Muslim Sisterhood members between 2013 and 2018 in Egypt. Findings suggest that the uprisings benefited the Sisters in terms of political participation, but that women who held gender worldviews similar to those of the Salafileaning MB male leadership ended up having greater public visibility in the 2012-2013 MB government. This contributed to the promotion of a conservative and motherhood-centred gender discourse in the political spaces that women and the movement seized after the 2011 uprisings.