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Association of objectively measured physical activity with vascular endothelial function in male adolescents

Sheridan, Sinead and Moyna, Niall orcid logoORCID: 0000-0003-1061-8528 (2015) Association of objectively measured physical activity with vascular endothelial function in male adolescents. In: 4th International Conference on Ambulatory Monitoring of Physical Activity and Movement (ICAMPAM '15), 10-12 June 2015, Limerick, Ireland.

Abstract
Purpose: Cardiovascular disease (CVD) begins in childhood primarily due to exposure to lifestyle-mediated risk factors such as inactivity and low cardiorespiratory fitness (CRF). Endothelial dysfunction is one of the earliest events in the development of CVD. Self-reported light intensity physical activity (LIPA) is positively associated with endothelial function (EF) in adolescents. The purpose of this study was to examine the relation between objectively measured physical activity (PA) and EF in healthy male adolescents. Methods: Low (n=8, VO2max = 40.4 ± 2.3 mL.kg1.min-1), moderate CRF (n=12,VO2max = 54.6 ± 3.9 mL.kg1.min-1) and high CRF (n=15, VO2max = 63.7 ± 4.0 mL.kg1.min-1) healthy males (mean age 15.77 ± 0.4; yr) participated in the study. High-resolution ultrasonography was used to assess endothelial dependent (EDD) in response to brachial artery flow mediated dilation. Participants wore a tri-axial ActivPAL accelerometer for 6 days. Total time spent in sitting, standing, LIPA, moderate-vigorous PA (MVPA) and steps per day was calculated using previously published methodology (Dowd et al., 2012). Results: EDD was significantly lower in low CRF than the high CRF group. Steps per day were significantly lower in low CRF (9251 ± 4113) than high CRF group (14007 ± 3176) (p<0.005). Time in sitting was significantly higher in low CRF than high CRF group (p<0.028). MVPA was significantly lower in low CRF than high CRF group (p<0.01). There was no significant difference in standing and LIPA between the groups. There was a significant positive relation between steps per day and % change (r=0.54, p<0.001) and absolute change in EDD (r= 0.60, p<0.001). Sitting was inversely related to % change (r=-0.497, p< 0.002) and absolute change in EDD (r=-0.49, p<0.003). There was a significant positive relation between MVPA and % change (r=0.47, p<0.005) and absolute change in EDD (r=0.57 p<0.000). Conclusion: There was a significant difference in steps per day, time spent sitting and in MVPA between low CRF and high CRF. MVPA was positively associated with EF in healthy adolescent males.
Metadata
Item Type:Conference or Workshop Item (Poster)
Event Type:Conference
Refereed:Yes
Uncontrolled Keywords:Cardiovascular disease (CVD); Cardiorespiratory fitness (CRF)
Subjects:Medical Sciences > Exercise
Medical Sciences > Health
Medical Sciences > Sports sciences
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Science and Health > School of Health and Human Performance
Research Initiatives and Centres > INSIGHT Centre for Data Analytics
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
Funders:SFI grant number SFI/12/RC/2289
ID Code:20673
Deposited On:24 Jun 2015 13:25 by Sinead Sheridan . Last Modified 26 Oct 2018 13:33
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