Following a short preview cf elecfcroanalytical techniques in drug analysis, a comparison was made betaken the use of mercury- and glassy carbon- based electrodes as electrochemical detection systems fear the determination of the antineoplastic agent cisplatin and its major hydrolysis products following separation by ion-pair chromatography. Differential pulse polarography was then applied to the determinaticn of the antibiotic ciprofloxacin in fcoiulated tablets. HMDEfe and carbcn paste electrodes (CPEs) were subsequently corpared for the determinaticn by adsorptive stripping voltanmetry (AdSV) of ciprofloxacin in urine. The electrochemical behaviour of four metabolites of ciprofloxacin at CPEs vas then investigated, in addition to the development of a flow-injecticn analysis assay with glassy carbon-based electrochanical detecticn to determine the antibiotic catpound in pharmaceutical preparations. Ftollowing a trief introduction to the analysis of anaerobic sealants and adhesives, an investigation vas made of the use of a cation exchange separation method, coupled to a detection systan involving post-column derivatisation with 4-(2-pyridylazo)resorcinol (PAR), for the determination of transition metals in anaerobic sealants. In anter to elucidate further the role of selected transition metals in araercbic cure mechanisms, a polarographic study of the reacticns of elemental ocpper and iron in the presoioe of l-acetyl-2-pherrylhydrazine and l-aoetyl-2^henyldiazine based cure systars was carried out.