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Genetically enhanced recombinant lectins for glyco-selective analysis and purification

Keogh, Damien, Larragy, Ruth, Thompson, Roisin, O'Connell, Michael, Clarke, Paul A. and O'Connor, Brendan orcid logoORCID: 0000-0002-8999-5184 (2011) Genetically enhanced recombinant lectins for glyco-selective analysis and purification. In: Research Review Day 2011, 16 Jun 2011, DCU, Dublin, Ireland.

Abstract
- Generation of a library of recombinant prokaryotic lectins (RPL’s) through random mutagenesis of the carbohydrate binding sites of bacterial lectins. - Characterisation of mutant lectins with respect to structure and specificity - Provision of mutant RPL’s with enhanced affinity and/or altered specificity, alongside wild-type RPL’s, for glycoprotein analysis and purification
Metadata
Item Type:Conference or Workshop Item (Poster)
Event Type:Conference
Refereed:Yes
Uncontrolled Keywords:lectins; recombinant prokaryotic lectins; RPLs
Subjects:Biological Sciences > Biotechnology
Biological Sciences > Biochemistry
Biological Sciences > Molecular biology
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Science and Health > School of Biotechnology
Research Initiatives and Centres > Irish Separation Science Cluster (ISSC)
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
Funders:Science Foundation Ireland
ID Code:17767
Deposited On:08 Feb 2013 11:42 by Brendan O'connor . Last Modified 03 Oct 2018 14:57
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